diff --git a/data/battle_scripts_1.s b/data/battle_scripts_1.s
index 01eabc6d5..2b94ffff5 100644
--- a/data/battle_scripts_1.s
+++ b/data/battle_scripts_1.s
@@ -3977,6 +3977,9 @@ BattleScript_EffectMeanLook::
 	accuracycheck BattleScript_ButItFailed, NO_ACC_CALC_CHECK_LOCK_ON
 	jumpifstatus2 BS_TARGET, STATUS2_ESCAPE_PREVENTION, BattleScript_ButItFailed
 	jumpifsubstituteblocks BattleScript_ButItFailed
+.if B_GHOSTS_ESCAPE >= GEN_6
+	jumpiftype BS_TARGET, TYPE_GHOST, BattleScript_ButItFailed
+.endif
 	attackanimation
 	waitanimation
 	setmoveeffect MOVE_EFFECT_PREVENT_ESCAPE
diff --git a/include/constants/battle_config.h b/include/constants/battle_config.h
index 02f873659..a3a385995 100644
--- a/include/constants/battle_config.h
+++ b/include/constants/battle_config.h
@@ -111,7 +111,7 @@
 #define B_ROUGH_SKIN_DMG            GEN_7 // In Gen4+, Rough Skin contact damage is 1/8th of max HP instead of 1/16th. This will also affect Iron Barbs.
 
 // Type settings
-#define B_GHOSTS_ESCAPE             GEN_7 // In Gen6+, Ghost-type Pokémon can escape even when blocked by abilities such as Shadow Tag.
+#define B_GHOSTS_ESCAPE             GEN_7 // In Gen6+, abilities like Shadow Tag or moves like Mean Look fail on Ghost-type Pokémon. They can also escape any Wild Battle.
 #define B_PARALYZE_ELECTRIC         GEN_7 // In Gen6+, Electric-type Pokémon can't be paralyzed.
 #define B_POWDER_GRASS              GEN_7 // In Gen6+, Grass-type Pokémon are immune to powder and spore moves.
 #define B_STEEL_RESISTANCES         GEN_7 // In Gen6+, Steel-type Pokémon are no longer resistant to Dark-type and Ghost-type moves.
diff --git a/src/battle_ai_main.c b/src/battle_ai_main.c
index a2d97f785..b8ed21e9d 100644
--- a/src/battle_ai_main.c
+++ b/src/battle_ai_main.c
@@ -3335,7 +3335,7 @@ static s16 AI_CheckViability(u8 battlerAtk, u8 battlerDef, u16 move, s16 score)
     case EFFECT_TRAP:
     case EFFECT_MEAN_LOOK:
         if (HasMoveEffect(battlerDef, EFFECT_RAPID_SPIN)
-          || IS_BATTLER_OF_TYPE(battlerDef, TYPE_GHOST)
+          || (B_GHOSTS_ESCAPE >= GEN_6 && IS_BATTLER_OF_TYPE(battlerDef, TYPE_GHOST))
           || gBattleMons[battlerDef].status2 & STATUS2_WRAPPED)
         {
             break; // in this case its a bad attacking move
diff --git a/src/battle_main.c b/src/battle_main.c
index dddd3cc79..271e97731 100644
--- a/src/battle_main.c
+++ b/src/battle_main.c
@@ -3705,6 +3705,10 @@ u8 IsRunningFromBattleImpossible(void)
 
     if (holdEffect == HOLD_EFFECT_CAN_ALWAYS_RUN)
         return 0;
+    #if B_GHOSTS_ESCAPE >= GEN_6
+        if (IS_BATTLER_OF_TYPE(gActiveBattler, TYPE_GHOST))
+            return 0;
+    #endif
     if (gBattleTypeFlags & BATTLE_TYPE_LINK)
         return 0;
     if (GetBattlerAbility(gActiveBattler) == ABILITY_RUN_AWAY)
diff --git a/src/battle_util.c b/src/battle_util.c
index 9515a1f32..275139f4f 100644
--- a/src/battle_util.c
+++ b/src/battle_util.c
@@ -621,6 +621,12 @@ bool8 TryRunFromBattle(u8 battler)
         gProtectStructs[battler].fleeFlag = 1;
         effect++;
     }
+    #if B_GHOSTS_ESCAPE >= GEN_6
+    else if (IS_BATTLER_OF_TYPE(battler, TYPE_GHOST))
+    {
+        effect++;
+    }
+    #endif
     else if (gBattleMons[battler].ability == ABILITY_RUN_AWAY)
     {
         if (InBattlePyramid())